Table 2. Acute toxicity according to CTCAE v3.0.
| Toxicity | Weekly cisplatin (n = 73) | Every three week cisplatin (n = 81) | P * | ||||||||
| Grade0 | Grade1 | Grade2 | Grade3 | Grade4 | Grade0 | Grade1 | Grade2 | Grade3 | Grade4 | ||
| Hematological | |||||||||||
| Leucopenia | 30 | 17 | 20 | 5 | 1 | 23 | 28 | 25 | 5 | 0 | 0.312 |
| Anemia | 58 | 9 | 4 | 2 | 0 | 61 | 17 | 3 | 0 | 0 | 0.233 |
| Thrombocytopenia | 62 | 4 | 2 | 3 | 2 | 74 | 2 | 2 | 2 | 1 | 0.583 |
| Non-hematological | |||||||||||
| Dermatitis | 0 | 59 | 13 | 1 | 0 | 0 | 54 | 24 | 3 | 0 | 0.121 |
| Mucositis | 0 | 29 | 21 | 23 | 0 | 0 | 23 | 34 | 23 | 1 | 0.139 |
| Dysphagia | 29 | 33 | 8 | 3 | 0 | 31 | 32 | 13 | 5 | 0 | 0.715 |
| Nausea/Vomiting | 32 | 24 | 17 | 0 | 0 | 36 | 27 | 15 | 3 | 0 | 0.295 |
| Xerostomia | 15 | 27 | 31 | 0 | 0 | 11 | 31 | 39 | 0 | 0 | 0.498 |
| Ototoxicity | 52 | 19 | 2 | 0 | 0 | 57 | 23 | 1 | 0 | 0 | 0.767 |
| Neurotoxicity | 70 | 2 | 1 | 0 | 0 | 77 | 3 | 1 | 0 | 0 | 0.632 |
*P-values were calculated with the chi-square test (or Fisher's exact test, if indicated).