Table 1. Baseline characteristics in rt-PA-treated and non-treated patients in the full cohort.
| rt-PA treated | rt-PA non-treated | P | |
| n = 153 | n = 800 | ||
| Age, years, median (IQR) | 86 (84–89) | 85 (83–88) | 0.09 |
| Female, n (%) | 96 (62.7) | 489 (61.1) | 0.71 |
| Risk factors, n (%) | |||
| Hypertension | 117 (76.5) | 602 (75.3) | 0.75 |
| Dyslipidemia | 47 (30.7) | 200 (25.0) | 0.15 |
| Diabetes | 28 (18.3) | 187 (23.4) | 0.16 |
| Atrial fibrillation | 94 (61.4) | 396 (49.5) | 0.007 |
| Smoking | 41 (26.8) | 198 (24.8) | 0.59 |
| Drinking | 26 (17.0) | 125 (15.6) | 0.67 |
| Chronic kidney disease, n (%) | 83 (54.2) | 446 (55.8) | 0.73 |
| Pre-stroke independency, n (%) | 108 (70.6) | 474 (59.3) | 0.007 |
| Previous stroke, n (%) | 29 (19.0) | 243 (30.4) | 0.003 |
| Previous ischemic heart disease, n (%) | 38 (24.8) | 165 (20.6) | 0.25 |
| Pre-stroke antithrombotic therapy, n (%) | 76 (49.7) | 352 (44.0) | 0.20 |
| Cardioembolic stroke, n (%) | 108 (70.6) | 406 (50.8) | <0.001 |
| Admission within 2 hours from onset, n (%) | 136 (88.9) | 586 (73.3) | <0.001 |
| Systolic blood pressure, mmHg, mean ± SD | 156±27 | 161±31 | 0.045 |
| NIHSS on admission, median (IQR) | 16 (9.5–21) | 9 (3–16.75) | <0.001 |
| Length of hospital stay, days, mean ± SD | 31.8±17.6 | 33.1±25.1 | 0.53 |
IQR: interquartile range. Pre-stroke independency was defined as mRS 0–1 before onset.