Table 4. Association between rt-PA and clinical outcomes in the PS-matched cohort.

	Events (%)		Unadjusted
	rt-PA-treated, n = 148	rt-PA non-treated, n = 148	OR	95% CI	P
Neurological improvement	91 (61.5)	56 (37.8)	2.67	1.61–4.40	<0.001
Good functional outcome	37 (25.0)	21 (14.2)	2.23	1.16–4.29	0.02
In-hospital mortality	13 (8.8)	32 (21.6)	0.30	0.13–0.65	0.003
Any ICH	17 (11.5)	12 (8.1)	1.45	0.68–3.13	0.34
Symptomatic ICH	7 (4.7)	6 (4.1)	1.17	0.39–3.47	0.78
Gastrointestinal bleeding	4 (2.7)	3 (2.0)	1.33	0.30–5.96	0.71

OR: odds ratio, CI: confidence interval, ICH: intracranial hemorrhage. Neurological improvement was defined as a ≥4 point decrease in the NIHSS score during hospitalization or a NIHSS score of 0 at discharge. Good functional outcome was defined as an mRS score of 0–2 at discharge.