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. 2014 Oct 16;9(10):e110542. doi: 10.1371/journal.pone.0110542

Figure 1. Inhibition of cell proliferation by AGEs.

Figure 1

SAS cells were treated with AGEs (0–400 µg/ml) or BSA (0–400 µg/ml) for 24 to 48 hours. The number of cells and proliferation were detected using trypan blue dye exclusion (A) and a WST-1 assay (B). AGEs significantly reduced the number of cells; BSA (as a negative control) increased viability (A). AGEs also inhibited cell proliferation (B). Treatment with AGEs (400 µg/ml; 0–4 hours) enhanced cell migration, while treatment with BSA did not (C).