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. 2014 Oct 7;7:1851–1867. doi: 10.2147/OTT.S68386

Table S1.

Categorized causes of deaths due to VEGFR-TKIs

Causes VEGFR-TKIs (%) Control (%)
Hemorrhage 5 (4.6) 4 (8.9)
Cerebrovascular accident 5 (4.6) 2 (4.4)
Renal failure 1 (0.9) 0 (0)
Neutropenia 5 (4.6) 0 (0)
Thromboembolism 9 (8.3) 3 (6.7)
Pulmonary disorders 4 (3.7) 6 (13.3)
Sudden death 3 (2.8) 0 (0)
Sepsis 5 (4.6) 2 (4.4)
Cardiopulmonary insufficiency 12 (11.1) 5 (11.1)
Hepatic failure 5 (4.6) 1 (2.2)
Gastrointestinal diseases 7 (6.5) 0 (0)
Other 4 (3.7) 6 (13.3)
Unknown 43 (39.8) 16 (35.6)
Total 108 (100) 45 (100)

Abbreviation: VEGFR-TKIs, vascular endothelial growth factor receptor tyrosine kinase inhibitors.