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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2014 Sep 3;3(6):445–463. doi: 10.1002/wdev.151

Figure 3. Induction in the Drosophila wing imaginal disc.

Figure 3

The normal, wildtype wing disc (left) has an organizing center that expresses Dpp (red) in response to signaling by Hh (blue), which originates in the Posterior (P) compartment. Levels of Dpp and Hh across the disc are depicted in the graph below. A disc (middle) with a clone in the P compartment that is deficient for engrailed function induces an ectopic organizing center and a duplication that includes both engrailed mutant and normal cells. Micrograph of wing with induced duplication and induced ectopic organizing center (right). (adapted from 7)