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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: J Cell Biochem. 2014 Dec;115(12):2103–2115. doi: 10.1002/jcb.24887

Fig. 1. Cell viability and clonal survival in cells treated with inhibitors of CK2.

Fig. 1

(A) Prostate cancer PC3-LN4 cells were treated with varying concentrations of TBB or TBCA (two inhibitors of CK2) over different periods of time (varying from 2 to 48 h) as indicated. Cell viability was determined relative to the controls in which no additions (untreated) were made. Statistical analysis of the data is as follows: * p < 0.001 to untreated, p < 0.0001 to DMSO; & p < 0.001 to untreated, p < 0.0001 to DMSO; # p = 0.04 to untreated. (B) Clonal survival of cells treated with 80 μM of TBB for varying periods of time (4 to 24 h). Representative colony formation results are shown on the right side while their quantitation is presented graphically on the left side of the panel. All other details are as described under Materials and Methods. Statistical analysis of the data is as follows: * p = 0.004 to DMSO; # p < 0.0001 to DMSO.