Figure 3. β-catenin is activated in human NSCLC tumors harboring EGFR mutants.
(A) Frequency distribution of nuclear β-catenin based on immunohistochemistry on human tissue microarray. P-value was calculated using Fisher's exact test. (B) Frequency of nuclear β-catenin in 4 pairs of pre- and post-TKIs NSCLC tumors. Each symbol represents an individual patient. The detailed information can be found in Supplementary Table. P-value was calculated using Student’s t-test.