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. 2014 Oct 8;8:1765–1780. doi: 10.2147/DDDT.S67980

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© 2014 Kamarudin et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Flow cytometric analysis of Δψm in NG108-15 cells.

Notes: (A) Representative dot plots of JC-1 aggregates (FL-2 red fluorescence) versus JC-1 monomers (FL-1 green fluorescence). Twenty thousand events were collected for each of the samples. (B) Bar chart showing the percentages of relative fluorescence intensity of Δψm in control, H₂O₂-only, and varying pretreatment concentrations of R-LA in NG108-15 cells. Values are means ± standard error and the asterisks indicate significantly different values from H₂O₂-treated cells (*P<0.05, n=4).

Abbreviations: LA, alpha-lipoic acid; R-LA, (R)-(+)-alpha-lipoic acid.