Fig. 7.
The tonic GABA receptor current reduces KC excitability. A: example traces showing the effect of PTX (10 μM, here and subsequently) on action potential (AP) firing evoked by ramp-current injection. Current-clamp recordings were made with K-gluc. int. soln. at resting Vm. B: example traces showing that in this KC, application of PTX caused spontaneous AP firing. C: individual and pooled data (n = 4) showing the small depolarization of resting Vm evoked by PTX. D: individual and pooled data (n = 4) showing that PTX reduces the amount of injected current required to evoke AP firing in KCs. *P < 0.05, statistical significance.