Table 1.
Participant characteristic in subjects with measured inflammation marker data, after weights were applied, and in eligible participants in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial screening arm
| Characteristic | No. (%) | Weighted, No. (%)* | PLCO screening arm, No. (%) |
|---|---|---|---|
| Total | 1819 | 58264 | 58264 |
| Sex | |||
| Female | 814 (44.8) | 28331 (48.6) | 28331 (48.6) |
| Male | 1005 (55.3) | 29933 (51.4) | 29933 (51.4) |
| Age group, y | |||
| ≤59 | 399 (21.9) | 18950 (32.5) | 20056 (34.4) |
| 60–64 | 533 (29.3) | 19911 (34.2) | 17954 (30.8) |
| 65–69 | 537 (29.5) | 11250 (19.3) | 12877 (22.1) |
| ≥70 | 350 (19.2) | 8153 (14.0) | 7377 (12.7) |
| BMI category, kg/m2 | |||
| <25 | 639 (35.1) | 18009 (30.9) | 18914 (32.4) |
| 25–30 | 792 (43.5) | 26939 (46.2) | 24753 (42.5) |
| ≥30 | 367 (20.2) | 12473 (21.4) | 14015 (24.1) |
| Missing | 21 (1.2) | 843 (1.4) | 582 (1.0) |
| Smoking status | |||
| Never | 548 (30.1) | 27219 (46.7) | 27389 (47.0) |
| Former | 857 (47.1) | 25381 (43.6) | 25032 (43.0) |
| Current | 414 (22.8) | 5664 (9.7) | 5843 (10.0) |
| Cigarettes per day in current smokers | |||
| 1–10 | 49 (11.8) | 836 (14.8) | 1007 (17.2) |
| 11–20 | 165 (39.9) | 1875 (33.1) | 2411 (41.3) |
| 21–30 | 109 (26.3) | 1760 (31.1) | 1452 (24.9) |
| 31–40 | 67 (16.2) | 495 (8.7) | 721 (12.3) |
| 41–60 | 22 (5.3) | 674 (11.9) | 221 (3.8) |
| 61+ | 2 (0.5) | 25 (0.4) | 31 (0.53) |
| Smoking duration in current smokers, y | |||
| <40 | 67 (16.2) | 1453 (25.6) | 1788 (30.6) |
| 40–44 | 126 (30.4) | 2461 (43.4) | 1903 (32.6) |
| 45–49 | 124 (30.0) | 1124 (19.8) | 1271 (21.8) |
| 50+ | 97 (23.4) | 627 (11.1) | 881 (15.1) |
| Years since quit in former smokers, y | |||
| <10 | 284 (33.1) | 4718 (18.6) | 5417 (21.6) |
| 10–19.9 | 233 (27.2) | 6603 (26.0) | 6480 (25.9) |
| 20–29.9 | 178 (20.8) | 7243 (28.5) | 6453 (25.8) |
| 30–39.9 | 127 (14.8) | 5193 (20.5) | 5223 (20.9) |
| 40+ | 35 (4.1) | 1625 (6.4) | 1459 (5.8) |
| Original case-control study | |||
| Lung cancer study | 998 (54.9) | 24410 (41.9) | --- |
| NHL study | 572 (31.5) | 24410 (41.9) | --- |
| Ovarian cancer study | 249 (13.7) | 9444 (16.2) | --- |
* Weighted estimates were calculated using the combined lung, non-Hodgkin’s lymphoma, and ovary weight. BMI = body mass index; NHL = non-Hodgkin’s lymphoma.