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. 2014 Aug 12;111(8):1614–1624. doi: 10.1038/bjc.2014.451

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Copyright © 2014 Cancer Research UK

From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Evaluation of whether plasma miR-25 level could reflect tumor dynamics. (A) Comparison of plasma miR-25 concentrations between preoperative and postoperative samples from ESCC patients. Plasma miR-25 levels were significantly lower in postoperative samples than in preoperative samples (P=0.0001). (B) Comparison of plasma miR-25 levels between postoperative and recurrence state samples from ESCC patients. In some patients from whom paired samples were collected after oesophagectomy and after recurrences, a significant re-elevation in plasma miR-25 levels was found at recurrence (P=0.0145).