Table 1.
Preoperative rotational thromboelastometry (ROTEM) parameters
| ROTEM parameter | Normal values | No thromboembolic complication (n =303), mean (SD) | Thromboembolic complication (n =10), mean (SD) | P -value | AUC ROC |
|---|---|---|---|---|---|
| EXTEM | |||||
| Clotting time, s | 42 to 74 | 55.1 (31.2) | 48.7 (16.9) | 0.19 | --- |
| Clot formation time, s | 46 to 148 | 87.1 (61.7) | 58.5 (16.6) | <0.001 | 0.74 |
| Alpha angle, degrees | 63 to 81 | 74.3 (6.9) | 78.4 (3.1) | 0.002 | 0.70 |
| Amplitude at 10/20 minutes, mm | 50 to 69 | 58.2 (8.7) | 64.0 (5.4) | 0.008 | 0.72 |
| Maximum clot firmness, mm | 49 to 71 | 65.0 (7.5) | 70.4 (5.2) | 0.009 | 0.73 |
| INTEM | |||||
| Clotting time, s | 137 to 246 | 171.5 (34.1) | 165.8 (24.6) | 0.11 | --- |
| Clot formation time, s | 71 to 82 | 72.2 (57.3) | 51.0 (11.4) | <0.001 | 0.75 |
| Alpha angle, degrees | 52 to 72 | 76.5 (5.5) | 79.4 (2.4) | 0.006 | 0.72 |
| Amplitude at 10/20 minutes, mm | 137 to 246 | 56.7 (7.8) | 63.0 (5.8) | 0.012 | 0.75 |
| Maximum clot firmness, mm | 52 to 72 | 62.8 (7.1) | 68.6 (6.0) | 0.02 | 0.74 |
| FIBTEM | |||||
| Clotting time, s | 43 to 69 | 53.3 (47.4) | 44.7 (13.1) | 0.11 | --- |
| Clot formation time, s | 339.9 (366.5) | 378.9 (606.0) | 0.12 | --- | |
| Alpha angle, degrees | 73.6 (6.6) | 77.0 (5.4) | 0.085 | --- | |
| Amplitude at 10/20 minutes, mm | 8 to 21 | 16.5 (6.8) | 23.7 (11.2) | 0.010 | --- |
| Maximum clot firmness, mm | 9 to 25 | 17.8 (7.6) | 24.8 (11.2) | 0.015 | --- |
For significant predictive tests, the area under the curve (AUC) of the receiver operating characteristic (ROC) curve is listed. EXTEM, extrinsic rotational thromboelastometry; INTEM, intrinsic rotational thromboelastometry; FIBTEM, fibrinogen rotational thromboelastometry; ns, not significant.