Table 2.
Frequency in |
||
Allele Size(bp) | Control Chromosomes(n = 102) | Deletion Chromosomes(n = 12) |
458 | .02 | 0 |
460 | .04 | 0 |
462 | .127 | .083a |
464 | .323 | .083a |
466 | .412 | .917 |
468 | .078 | 0 |
Note.— The expected heterozygosity of MHB001 is calculated to be 70.2%. Fisher’s exact test of frequencies of 466-bp allele in deletion and control chromosomes showed a significant difference (P=.0012 in a two-tailed test).
The carrier NN2 has the genotype of 462/464, with the deletion chromosome having either 462-bp or 464-bp allele (see table 1).