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. 2014 Oct 11;14:390. doi: 10.1186/1472-6882-14-390

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© Nakashima et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Consumption of Chlorella reduced oxidative stress and muscle tissue injury in ALDH2*2 Tg mice. Wild type (n =7) and control ALDH2*2 Tg mice (n =8) were fed a basal diet, while the CSD ALDH2*2 Tg mice received a Chlorella-supplemented diet (n =8). Urinary 15-isoprostane levels were measured 2 and 4 months after the initial Chlorella administration (a). After 6 months of consuming the Chlorella diet, MDA and HAE were measured in the quadriceps muscle (b). The levels of CPK (c) and CKMB (d) detectable in plasma were measured 6 months after initial Chlorella administration. Values are the mean ± SD, *p <0.05 and **p <0.01: significant vs. Control; ^# p <0.01: significant vs. Wild type.