Table 3.
Cancer risk for female T2DM patients by cancer site and follow-up period
| Follow-up period | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cancer site | Total | 1st year | 2 - 5 years | ≥5 years | |||||||||
| Obs | SIR | 95% CI | Obs | SIR | 95% CI | Obs | SIR | 95% CI | Obs | SIR | 95% CI | ||
| Head & Neck | [C00-C14; C30-C32] | 2 | 0.40 | (0.05, 1.46) | 0 | 0.00 | (0.00, 8.14) | 0 | 0.00 | (0.00, 2.30) | 2 | 0.69 | (0.08, 2.51) |
| Stomach | [C16] | 10 | 1.07 | (0.51, 1.97) | 1 | 1.18 | (0.03, 6.58) | 3 | 1.01 | (0.21, 2.94) | 6 | 1.09 | (0.40, 2.36) |
| Colorectum | [C18-C21] | 27 | 0.94 | (0.62, 1.36) | 4 | 1.58 | (0.43, 4.05) | 7 | 0.77 | (0.31, 1.59) | 16 | 0.93 | (0.53, 1.51) |
| Liver | [C22] | 7 | 2.40 | (0.96, 4.94) | 1 | 4.07 | (0.10, 22.70) | 0 | 0.00 | (0.00, 4.12) | 6 | 3.37 | (1.24, 7.34) |
| Pancreas | [C25] | 16 | 1.78 | (1.02, 2.89) | 7 | 9.51 | (3.82, 19.59) | 4 | 1.48 | (0.40, 3.79) | 5 | 0.90 | (0.29, 2.11) |
| Lung | [C33-C34] | 15 | 0.79 | (0.44, 1.30) | 2 | 1.18 | (0.14, 4.27) | 4 | 0.66 | (0.18, 1.69) | 9 | 0.80 | (0.37, 1.52) |
| Melanoma | [C43] | 9 | 0.82 | (0.37, 1.55) | 1 | 0.93 | (0.02, 5.19) | 3 | 0.81 | (0.17, 2.35) | 5 | 0.81 | (0.26, 1.88) |
| Breast | [C50] | 72 | 1.13 | (0.88, 1.42) | 12 | 1.94 | (1.00, 3.39) | 21 | 0.98 | (0.60, 1.49) | 39 | 1.08 | (0.77, 1.48) |
| Breast postmenopausal | [C50] | 70 | 1.18 | (0.92, 1.49) | 11 | 1.99 | (1.00, 3.57) | 20 | 1.02 | (0.62, 1.58) | 39 | 1.14 | (0.81, 1.55) |
| Cervix uteri | [C53] | 10 | 1.81 | (0.87, 3.32) | 4 | 6.22 | (1.69, 15.92) | 2 | 0.96 | (0.12, 3.47) | 4 | 1.42 | (0.39, 3.65) |
| Corpus uteri | [C54] | 24 | 1.79 | (1.15, 2.66) | 4 | 3.14 | (0.86, 8.05) | 5 | 1.13 | (0.37, 2.64) | 15 | 1.94 | (1.09, 3.20) |
| Ovary | [C56] | 7 | 0.63 | (0.25, 1.29) | 1 | 0.95 | (0.02, 5.31) | 1 | 0.27 | (0.01, 1.51) | 5 | 0.78 | (0.25, 1.81) |
| Bladder | [C67] | 4 | 0.89 | (0.24, 2.29) | 0 | 0.00 | (0.00, 9.71) | 1 | 0.70 | (0.02, 3.92) | 3 | 1.12 | (0.23, 3.29) |
| Kidney | [C64-C65] | 10 | 1.45 | (0.70, 2.67) | 1 | 1.57 | (0.04, 8.74) | 4 | 1.79 | (0.49, 4.59) | 5 | 1.24 | (0.40, 2.90) |
| Thyroid | [C73] | 8 | 1.65 | (0.71, 3.25) | 2 | 3.86 | (0.47, 13.95) | 3 | 1.69 | (0.35, 4.94) | 3 | 1.17 | (0.24, 3.42) |
| Brain | [C47; C70-C72] | 0 | 0.00 | (0.00, 1.18) | 0 | 0.00 | (0.00, 12.58) | 0 | 0.00 | (0.00, 3.55) | 0 | 0.00 | (0.00, 2.05) |
| Haem&Lymph1) | [C81-C85; C88; C90-C96; D45-D47] | 26 | 1.28 | (0.84, 1.87) | 3 | 1.65 | (0.34, 4.83) | 5 | 0.78 | (0.25, 1.82) | 18 | 1.49 | (0.88, 2.35) |
| All except NMSC | [C00-C97; D45-D47; exc. C44] | 234 | 1.05 | (0.92, 1.20) | 42 | 1.96 | (1.42, 2.66) | 61 | 0.82 | (0.63, 1.06) | 131 | 1.03 | (0.86, 1.23) |
1)Neoplasms in the haematologic/lymphatic system.