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Constitutive transducin activation induces the UPR. A, Western blots of whole retinal homogenates prepared from the indicated mice probed with the indicated antibodies. The signal intensity was quantified. B and C, the relative fold changes of protein levels were normalized to actin and to the dark-adapted values and plotted for ARR1−/− (B) and BALB/c (C) retinas (means ± S.E., n ≥ 3).
