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Effect of CAV-1 KO and Los (L) on ANG II-induced activation of PKC-α in PTs of WT and CAV-1 KO mice. Note that p-PKC-α (Ser657) was increased in the PT by ANG II in WT mice but not in CAV-1 KO mice. **P < 0.01 vs. control (C); ++P < 0.01 vs. ANG II.
