Fig. 6.

Effects of CAV-1 on the in vivo uptake of Alexa fluor 488 ANG II conjugate in PTs of WT and CAV-1 KO mice. A–C: PT uptake of Alexa fluor 488 ANG II conjugate in a representative WT mouse. D–F: PT uptake of Alexa fluor 488 ANG II conjugate in a representative CAV-1 KO mouse. G: semiquantitative data on the uptake of Alexa fluor 488 ANG II conjugate in PTs of WT and CAV-1 KO mice, respectively, expressed as AFU with WT mice at 100. Little uptake occurred in the glumeruli (G) in the cortex. Red shows DAPI-stained nuclei in the renal cortex. **P < 0.01 vs. WT mice. Magnification: ×10.