Table 1.

Basal SBP and renal functional phenotypes in WT and CAV-1 KO mice

Parameters	WT Mice	CAV-1 KO Mice
Number of mice/group	11	12
Body weight, g	25.4 ± 0.6	23.8 ± 0.3
Heart weight-to-body weight ratio, ×100	0.52 ± 0.02	0.59 ± 0.03*
Kidney weight-to-body weight ratio, ×100	1.18 ± 0.02	1.44 ± 0.06†
Drinking, ml/24 h	3.42 ± 0.07	3.32 ± 0.70
SBP, mmHg	114 ± 2	122 ± 3*
Urine excretion, ml/24 h	1.19 ± 0.05	1.30 ± 0.17
Urinary Na+ excretion, μmol/24 h	203.8 ± 5.2	210.2 ± 10.2
Urinary K+ excretion, μmol/24 h	408.7 ± 9.9	293.8 ± 16.4*

Values are means ± SE. WT, wild type; CAV-1, caveolin-1; KO, knockout; SBP, systolic blood pressure.

^*P < 0.05 and

^†P < 0.01 vs. WT mice.