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PPAR antagonism revives renal fibrosis and inflammation in sEH-KO mice. Expression of α-SMA, p-Smad3, and p-p65 in WT and sEH-KO mouse kidneys treated with either vehicle or mixture of PPAR isoform antagonists at 10 days after UUO using Western blot. The bands were quantified using Lab Works analysis software. Error bars represent SD (n = 4). †P < 0.05 vs. vehicle.
