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Loss of sEH restricts the reduction of peroxisome proliferator-activated receptors (PPARs) activity induced by UUO. The activity of PPAR isoforms in kidneys in WT or sEH-KO mice after sham operation or UUO was assayed using PPARα, β/δ, γ transcription factor assay kit. Error bars represent SD (n = 6). *P < 0.05 vs. sham. #P < 0.05 vs. WT. §P < 0.05 vs. 3 days.
