Table 2.

GI motility of OTRKO and OT

Mouse, n = 6/group	GITT, min	Gastric Emptying, %	Small Bowel Transit, cm	Bead Expulsion, s
OTRKO vs. WT (C57BL/6)
WT	160.3 ± 10	86.6 ± 8.9	3.8 ± 0.7	509 ± 73
OTRKO	126.5 ± 5.3*	92.1 ± 7.2	3.5 ± 0.9	1326 ± 312*
Exogenous OT vs. saline in C57BL/6 mice
Saline	87.3 ± 5.8	98.4 ± 0.4	3.8 ± 0.7	630 ± 116.7
OT	115.0 ± 9.0†	86.9 ± 2.8†	4.0 ± 0.5	600 ± 73.5
Exogenous OT vs. saline in BALB/c mice
Saline	83.8 ± 15.0	97.0 ± 0.9	3.9 ± 0.3	357.7 ± 108
OT	185.3 ± 30.4†	78.4 ± 5.8†	2.7 ± 0.2†	329.4 ± 80.5

Values are means ± SE.

^*OTRKO significantly different from WT.

^†OT significantly different from saline. GITT, gastrointestinal transit time.