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. 2014 Nov;28(11):4677–4685. doi: 10.1096/fj.14-251652

Figure 5.

Figure 5.

Flow-induced [Ca2+]i change in HEK293 cells expressing 1 TRP isoform (TRPV4, TRPC1, or TRPP2) or coexpressing 2 TRPs. A) Representative traces showing a flow-induced [Ca2+]i change in HEK293 cells that expressed TRPV4, TRPC1, or TRPP2. B) Summary showing the maximum increase in flow-induced [Ca2+]i response. Cells expressed TRPV4, TRPC1, or TRPP2 or coexpressed 2 TRPs. All cells were bathed in NPSS containing 1% BSA. Means ± se (n=7–9 transfection experiments, ∼40 cells/experiment). *P < 0.01 vs. vector.