Figure 8.
Effect of lenti-TRPP2D511V on flow-induced vascular dilation in isolated small mesenteric artery segments. A, B) Representative traces of flow-induced arterial dilation in arteries pretreated with lentivector (A) or lenti-TRPP2D511V (B). Arteries were precontracted with phenylephrine (Phe), followed by a flow shear force of ∼5 dyn/cm2. Horizontal lines indicate the period when intraluminal flow was applied. C) Data summary for panels A (open bar) and B (solid bar). Means ± se (n=6). *P < 0.05.