A) Secreted factor levels detected in MCF10a-conditioned medium. B) Secreted factor levels detected in HMEC-SR-conditioned medium. C) Secreted factor levels detected in HMEC-15-htert-conditioned medium. FGF-2, fibroblast growth factor-2; G-CSF, granulocyte-colony stimulating factor; MCP-1, monocyte chemotactic protein-1. Error bars = sd. Solid horizontal line represents the 2D culture condition, which is set to 1. Statistical significance between conditions was determined as a value of P < 0.05 using a Student's t test. This is denoted in each graph by a letter or number above the bar, corresponding to the comparative condition indicated in the legend.