Figure 2.
Inflammatory cell numbers were determined in BALF. WT, Epac1−/−, Epac2−/−, and PLCε−/− mice were exposed to air or CS for 4 d, after which BALF was collected. The level of total inflammatory cells (A), macrophages (B), lymphocytes (C), and neutrophils (D) in BALF were analyzed. Data are presented as means ± sem of 6–10 animals. *P < 0.05, **P < 0.01, ***P < 0.001 vs. basal control; #P < 0.05 vs. WT exposed to CS.