Fig. 1.

Schematic representation of the two salt-sensitive (SS)-12^BN congenic strains that were generated by introgressing segments of the SS chromosome 12 (black) into the genetic background of the SS-12^BN consomic rat (white) by marker-assisted selection. Line Ca is a smaller congenic derived from line C. Mean arterial pressures from 9 AM to 12 PM while on 0.3% NaCl are shown. The sample size for each group is shown. The thin black bars represent chromosomal regions that could be either Brown Norway (BN) or SS. *P < 0.05 vs. SS-12^BN. All other chromosomes are SS. SSLP, simple sequence length polymorphism.