Table 1. Regional Correlations Between Self-Reported Withdrawal Symptoms and CBF for the Main Effect of Smoke (ABST—DENIC).
| Brain region | Peak x, y, z | Brodmann | T-max | KE |
|---|---|---|---|---|
| Craving (positive) | ||||
| L superior frontal gyrus/frontal pole | −24, 44, 42 | 9, 46 | 5.95 | 588 |
| R frontal pole/middle frontal gyrus | 36, 40, 24 | 9, 44, 46 | 4.05 | 314 |
| R middle frontal gyrus | 32, 8, 41 | 6, 8, 9, 44 | 4.03 | 202 |
| R frontal pole | 10, 50, 40 | 9 | 3.80 | 170 |
| R frontal pole/middle frontal gyrus | 28, 38, 50 | 8, 9 | 3.71 | 169 |
| R postcentral & precentral gyrus, precuneus cortex | 12, −44, 63 | 2, 3, 4, 5, 6, 7 | 4.89 | 3322 |
| R lateral occipital cortex | 32, −72, 39 | 7, 19 | 3.65 | 178 |
| R temporal fusiform cortex/parahippocampal gyrus | 32, −6, −49 | 20, 36 | 5.65 | 756 |
| R middle temporal gyrus | 66, −20, −13 | 20, 21, 22 | 4.55 | 374 |
| L middle temporal gyrus | −58, −14, −17 | 20, 21, 22 | 4.02 | 160 |
| R middle temporal gyrus/supramarginal gyrus | 46, −36, 3 | 21, 22 | 3.74 | 165 |
| L parahippocampal gyrus | −18, −14, −29 | 35, 36 | 3.52 | 192 |
| L cerebellum | −20, −56, −29 | 3.91 | 883 | |
| R cerebellum | 28, −66, −21 | 3.65 | 993 | |
| Negative affect (positive) | ||||
| R middle temporal gyrus | 68, −16, −11 | 20, 21, 22 | 4.18 | 175 |
| R parahippocampal gyrus | 30, −2, −33 | 20, 36 | 4.11 | 485 |
| L cerebellum | −10, −40, −29 | 3.74 | 648 | |
| Habit withdrawal (negative) | ||||
| L brainstem/cerebellum | −8, −28, −27 | 4.63 | 494 | |
Abbreviations: L, left, R, right.
Directions of the relationships are indicated as positive or negative. Cluster corrected threshold p<0.05 (p<0.005 uncorrected, ⩾157-voxel cluster of contiguous significant voxels).