Table 3.
Frequency of Creld1-genotypes during embryogenesis.
| Creld1 Genotypes | |||
|---|---|---|---|
| Embryonic Day | −/− | +/− | +/+ |
| 9.5 | 51 (20.4%) | 125 (50%) | 74 (29.6%) |
| 10.5 | 92 (22.2%) | 214 (51.6%) | 109 (26.3%) |
| 11.5 | 12 (24%)a | 28 (56%) | 10 (20%) |
| 12.5 | 3 (15%)b | 11 (55%) | 6 (30%) |
a
The E11.5 Creld1−/− embryos did not have beating hearts.
b
The E12.5 Creld1−/− tissue found at this stage was being reabsorbed.
Incidence of Creld1genotypes during mouse embryogenesis. E10.5 and E9.5 Creld1−/− embryos were alive and in Mendelian ratio. E11.5 Creld1−/− embryos were in concordance with Mendelian ratio but dead. By E12.5 little Creld1−/− tissue was identifiable and by E13.5 no Creld1−/− embryonic tissue was found. Ratio conformance tested by chi-square analyses (E9.5, χ2 = 4.232, p-value = 0.1205; E10.5 embryos, χ2 = 1.800, p-value = 0.4066; E11.5 embryos, χ2 = 0.880, p-value = 0.6440).