Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Breast pain
RCT	147 pre-menopausal women with breast pain	Mean days with severe breast pain per cycle (pain measured using the Cardiff breast pain chart) 6 months 17.6 to 5.9 (67% reduction from baseline) with goserelin injection 18.4 to 12.0 (35% reduction from baseline) with placebo injection	P = 0.0001	Effect size not calculated	goserelin injection