Skip to main content
. 2003 Nov 20;8(1):R1–R11. doi: 10.1186/cc2398

Table 4.

Mean percentage of hours of optimal sedation (intent to treat population)

Remifentanil (n = 77) Fentanyl (n = 75) P
Maintenance phase
 Median duration (h; range) 13.7 (2.7–73.0) 14.2 (0.3–73.3) NT
 Mean (range) % of hours of optimal sedation 88.3 (0.0–100.0) 89.3 (32.5–100.0) NS*
 Ratio of between-patient variability (fentanyl versus remifentanil) 1.09 NS
Maintenance phase (excluding the patient in the remifentanil group who failed to achieve an SAS score of 4)
 Mean (range) % of hours of optimal sedation 89.5 (45.2–100.0) 89.3 (32.5–100.0) NS*
 Ratio of between-patient variability (fentanyl versus remifentanil) 1.84 0.009
Extubation phase
 Mean (range) % of hours of optimal sedation 87.7 (0.0–100.0) 95.5 (40.0–100.0) NT
Postextubation phase
 Mean (range) % of hours of optimal sedation 92.3 (0.0–100.0) 95.7 (32.3–100.0) NT
Post-treatment period
 Mean (range) % of hours of optimal sedation 92.6 (0.0–100.0) 91.6 (0.0–100.0) NT

*Unpaired t-test on arcsine square root transformed data; F test. NS, not significant; NT, not tested; SAS, Sedation–Agitation Scale.

HHS Vulnerability Disclosure