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. 2012 Nov 15;7(32):2522–2527. doi: 10.3969/j.issn.1673-5374.2012.32.006

Figure 2.

Figure 2

Ultrastructural nerve pathology (transmission electron microscopy, × 5 000) in CMT1A and HNPP.

(A) CMT1A: Superficial peroneal nerve pathology indicated by irregular thickening of the myelin sheath of myelinated nerve fibers, onion-like structures (→), and enlarged gaps in the myelin sheath surrounding the axons (↓).

(B) HNPP: Superficial peroneal nerve pathology indicated by a degenerated myelin sheath of myelinated nerve fibers, irregular thickening, loosing, edema, and a ‘mouse-nibbled’ appearance (←).

CMT1: Charcot-Marie-Tooth disease myelin sheath type; HNPP: hereditary neuropathy with liability to pressure palsies.