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Routinely pre-analytical and analytical approaches for farm animal serum proteomic studies. Serum samples could be pre-treated (A) to reduce the high dynamic range in protein concentration, or not pre-treated (B,C) and, subsequently, analyzed through electrophoretic, chromatographic and mass spectrometric platforms. The large amount of data produced are, then, processed by sophisticated bioinformatic algorithms for qualitative and quantitative proteomic analysis.
