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. 2014 Aug 25;15(9):14949–14966. doi: 10.3390/ijms150914949

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Possible mechanisms of the anti-metastatic effects of pomegranate. Possible mechanisms include increasing cell adhesion, decreasing cell migration and C–X–C motif chemokine 12 (CXCL12) chemotaxis, targeting hyaluronan and arachidonic acid pathway, and reducing matrix metalloproteinases (MMPs) production.