Figure 1.

Unsaturated Fatty Acid Metabolism in the n-3, n-6, n-7, and n-9 Pathways. Enzymes are in italics and the vertical dashed line indicates the common reactions that they catalyze. Fatty acids that show consistently abnormal values in blood from cystic fibrosis patients are indicated in red. PA, palmitate; POA, palmitoleate; MA, Mead acid; LA, linoleate; AA, arachidonate; DPA, docosapentaenoate; LNA, alpha-linolenate; EPA, eicosapentaenoate; DHA, docosapentaenoate; Δ9D, Δ9-desaturase; Δ6D, Δ6-desaturase, EL5, elongase 5; Δ5D, Δ5-desaturase; EL2, elongase 2; βOX, β-oxidation.