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. 2014 Aug 25;15(9):14935–14948. doi: 10.3390/ijms150914935

Figure 4.

Figure 4

Synergistic effect of targeting Nanog combined with of cisplatin treatment decreased oncogenicity. Secondary spheroids formation (A); invasion ability (B) and colony-forming ability (C) were assessed in HNSCC-SCs treated with either sh-Nanog lentiviruses or cisplatin chemotherapy or both; and (D) Annexin V-positive cells were assessed in HNSCC-CSCs treated with either sh-Nanog lentiviruses or cisplatin chemotherapy or both. * p < 0.05 sh-Nanog-1 vs. sh-Luc; # p < 0.05 sh-Nanog-1 + Cisplatin vs. sh-Nanog-1 alone.