Table 2.
Clinical studies analyzing characteristics and survival of patients diagnosed with brain metastases originating from esophageal cancer.
| Inc | n | Age (Years) | Male | ECM | BM > 1 | Resection | OS (Months) | OS Resection (Months) | Reference |
|---|---|---|---|---|---|---|---|---|---|
| 1.4% | 36 | 62 | 92% | 53% | 53% | 33% | 3.9 | 9.6 | [22] |
| 1.7% | 27 | 62 | 100% | 70% | 52% | 37% | 3.8 | 3.8–9.6 | [25] |
| 3.4% | 29 | n/a | n/a | 44% | 52% | 21% | 3.5 | improved | [23] |
| 2.1% | 17 | 58 | n/a | 76% | 35% | 59% | n/a | improved | [26] |
| 2.7% | 12 | 64 | 92% | 75% | 67% | 17% | 2.1 | 1.2–7.0 | [27] |
| 3.9% | 20 | n/a | n/a | 45% | 40% | 60% | 10.5 | n/a | [24] |
| 1.6% | 26 | 62 | 96% | 69% | 54% | 19% | 4.2 | 7.0 | [21] |
Inc = Incidence of brain metastases in the respective study; n = number of patients enrolled in the study; Male = Percentage of male patients of the patient cohort; ECM = percentage of patients diagnosed with extra-cranial metastases; BM > 1 = percentage of patients diagnosed with more than one brain metastases; Resection = percentage of patients that received surgical resection of brain metastases; OS = median survival of all patient diagnosed with brain metastases within the respective study; OS Resection = median survival of the patients who received surgical resection of brain metastases; n/a = data not available.