Figure 5.

Stretch dependency of sVEGFR-1 expression in C-28/I2. Cells were stretched for 12 h with cyclic waveforms and a variety of relative strains. Expression of soluble decoy VEGF receptor: sVEGFR-1 was analyzed directly after straining (t₀) (A) or 24 h post straining (B), using cyclic square waveform at 0.5 Hz. Relative percentages of stretching are indicated (i.e., 1%, 4% or 8%, respectively). Unstrained controls (ctrl) were used to normalize data (set to 1). * and *** indicate significance levels of p ≤ 0.05 and p ≤ 0.001 respectively, n = 3.