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. 2014 Aug 26;15(9):15011–15025. doi: 10.3390/ijms150915011

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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(a) (I) The representative immunohistochemistry (IHC) staining of MRC2 in HCC tissues. MRC2 protein located in both cell membrane (black arrow) and cytoplasm (white arrow); (II) The representative IHC staining of MRC2 in adjacent liver tissues; (III) The negative staining of MRC2 in HCC tissues; (b) The western immunoblotting results of MRC2 in 3 pairs of representative HCC tissues (T) and adjacent liver tissues (N); (c) The IHC scores of MRC2 in HCC tissues were significantly higher than one in adjacent liver tissues (p < 0.001); and (d) The comparison of Kaplan–Meier survival curves showed that patients with higher MRC2 expression in HCC tissues had worse prognosis after liver resection (HR = 3.071; 95% CI: 1.357, 6.951; p = 0.007).