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Histomorphological sections obtained from distal femurs of 14-week-old male C57BL/6J (2A, n=5), male C57BL/6J Cftr-/- (2B, n=5), female C57BL/6J (2C, n=9) and female C57BL/6J Cftr-/- (2D, n=5) mice at 20X. C57BL/6J Cftr-/- mice have decreased trabecular bone volume as well as decreased trabecular width. The reduced number of black-stained cancellous bone spicules is especially apparent in the female C57BL/6J Cftr-/- mouse. Magnification=20x, Scale bars= 1 mm
