Table 1.
Baseline patient characteristics (n = 5029) and hospitalization burden
| Characteristic | No. (%) | Percent Patients Spending ≥25% of Remaining Life Hospitalized |
|---|---|---|
| All patients | 5029 (100) | 21.7 |
| Age at diagnosis, y | ||
| 65 to ≤74 | 2597 (51.6) | 18.2 |
| 75 to ≤84 | 2038 (40.5) | 25.8 |
| 85+ | 394 (7.8) | 24.4 |
| Gender | ||
| Male | 2595 (51.6) | 21.7 |
| Female | 2434 (48.4) | 21.7 |
| Race/ethnicity | ||
| White, non-Hispanic | 4441(88.3) | 21.1 |
| Hispanic | 280 (5.6) | 23.6 |
| Black | 187 (3.7) | 33.7 |
| Asian | 67 (1.3) | 19.4 |
| Other | 54 (1.1) | 24.1 |
| Marital status | ||
| Married | 3044 (60.5) | 20.3 |
| Unmarried | 638 (12.7) | 23.4 |
| Unknown | 1347 (26.8) | 24.1 |
| Modified Charlson comorbidity score (13) | ||
| 0 | 3077 (61.2) | 18.7 |
| 1 | 1280 (25.5) | 22.7 |
| 2+ | 672 (13.4) | 33.8 |
| Year of diagnosis | ||
| 1999–2001 | 1383 (27.5) | 21.7 |
| 2002–2004 | 1835 (36.5) | 21.6 |
| 2005–2007 | 1811 (36.0) | 21.9 |
| Census tract income level | ||
| Lower income (<median) | 1733 (34.5) | 22.3 |
| Higher income (≥median) | 3296 (65.5) | 21.4 |
| SEER registry region | ||
| Northeast | 364 (7.2) | 20.9 |
| South | 520 (10.3) | 19.0 |
| Midwest | 804(16.0) | 24.1 |
| West | 3341(66.4) | 21.7 |
| Tumor location | ||
| 1 brain lobe | 3752 (74.6) | 21.0 |
| 2+ brain lobes | 941 (18.7) | 24.8 |
| Other | 336 (6.7) | 21.7 |
| Surgery | ||
| Extensive (GTR) | 1293 (25.7) | 17.1 |
| Limited (biopsy/STR) | 3736 (74.3) | 23.3 |
| Radiotherapy delivered | ||
| Yes | 3637 (72.3) | 16.3 |
| No | 1392 (27.7) | 36.0 |
| Temozolomide delivered | ||
| Yes | 880 (17.5) | 6.1 |
| Before March 2005 | 402 (8.0) | |
| March 2005 or later | 478 (9.5) | |
| No | 4149 (82.5) | 25.0 |
| Other chemotherapy delivered | ||
| Yes | 1022 (20.3) | 10.5 |
| No | 4007 (79.7) | 24.6 |
| Discharge disposition after index hospitalization for GBM diagnosis | ||
| Home | 2300 (45.7) | 11.1 |
| Home with services | 588 (11.7) | 14.6 |
| Rehabilitation | 483 (9.6) | 33.1 |
| ICF/SNF | 921 (18.3) | 30.6 |
| Hospice | 182 (3.6) | 36.3 |
| Expired | 132 (2.6) | 100.0 |
| Cumulative days hospitalized, including index hospitalization and all rehospitalizations, median (IQR) | 15 (8–26) | 25 (16–39) |
Abbreviations: GTR, gross total resection; STR, subtotal resection; ICF, intermediate care facility; SNF, skilled nursing facility; IQR, interquartile range.