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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Drugs. 2014 Sep;74(14):1573–1585. doi: 10.1007/s40265-014-0286-5

TABLE 2.

Anidulafungin and micafungin ECVs for eight species of Candida1

Antifungal
agent		 Species No. of
isolates		 MIC (µg/ml) ECV (µg/ml)2
Range Mode ≥95% ≥97.5% ≥99%
Anidulafungin C. albicans 8,210 0.008–2 0.03 0.06 0.12 0.12
C. glabrata 2,680 0.008–4 0.06 0.12 0.12 0.25
C. parapsilosis 3,976 0.008–8 2 4 8 8
C. tropicalis 2,042 0.008–2 0.03 0.12 0.12 0.12
C. krusei 322 0.008–2 0.06 0.12 0.25 0.25
C. lusitaniae 234 0.008–1 0.25 1 1 1
C. guilliermondii 222 0.03–4 1 4 8 8
C. dubliniensis 131 0.015–4 0.03 0.12 0.12 0.12
Micafungin C. albicans 7,874 0.008–4 0.015 0.03 0.03 0.03
C. glabrata 3,102 0.008–4 0.015 0.03 0.03 0.03
C. parapsilosis 3,484 0.015–4 1 2 4 4
C. tropicalis 1,605 0.008–8 0.015 0.06 0.06 0.12
C. krusei 617 0.015–1 0.06 0.25 0.25 0.25
C. lusitaniae 258 0.008–≥16 0.25 0.5 0.5 1
C. guilliermondii 234 0.015–8 0.5 2 2 4
C. dubliniensis 117 0.008–8 0.06 0.12 0.12 0.12
1

Adapted from Pfaller et al. 2014 [27]

2

Calculated ECVs comprising ≥95%, ≥97.5%, or ≥99% of the statistically modeled MIC population.