Table V.
Variable | Univariate | Multivariate | |
---|---|---|---|
P | OR (95% CI) | P | |
Age | 0.40 | ||
Bilateral neck dissections (yes vs. no) | 0.011 | 2.07 (0.29 - 14.57) | 0.47 |
Chemotherapy received (yes vs. no) | 0.034 | 5.53 (0.45 - 68.66) | 0.18 |
Comorbidity scale (2-3 vs 0-1)** | 0.61 | 1.67 (0.19 - 14.81) | 0.64 |
Converted to open (yes vs. no)+ | 0.35 | 5.61 (0.17 - 187.80) | 0.34 |
Cranial nerve XII injury (yes vs. no) | * | ||
Free flap (yes vs. no) | * | ||
Locoregional recurrence (yes vs. no) | 0.051 | 12.48 (0.61 - 255.57) | 0.10 |
Re-resections (yes vs. no)++ | 0.45 | ||
N stage (N2-3 vs N0-1) | 0.64 | ||
p16 (positive vs negative) | 0.37 | ||
RT modality (IMRT vs 2D) | >0.99 | ||
RT to primary site (yes vs. no) | >0.99 | ||
RT to ipsilateral neck (yes vs. no) | >0.99 | ||
RT to contralateral neck (yes vs. no) | >0.99 | ||
RT to all 3 sites (yes vs. no) | >0.99 | ||
RT dosage to primary site | 0.67 | ||
RT dosage to ipsilateral neck | 0.13 | ||
RT dosage to contralateral neck | 0.14 | ||
Tumor subsite (BOT vs tonsil) | 0.49 | 1.91 (0.27 - 13.46) | 0.52 |
T stage (T3-4 vs. T1-2) | < 0.0001 | 15.38 (1.57 - 150.90) | 0.019 |
OR = odds ratio, BOT = base of tongue, RT = radiation therapy
Not sufficient events for accurate analysis T stage = tumor stage, N stage = nodal stage, CN = cranial nerve, 2D = two dimensional, IMRT = intensity modulated radiation therapy
per ACE-27 instrument, see text for explanation
conversion of the initial surgery to an open procedure for cancer clearance
second look surgery for revision of margins