Table V.

Univariate and multivariate analyses for persistently poor swallowing

Variable	Univariate	Multivariate
	P	OR (95% CI)	P
Age	0.40
Bilateral neck dissections (yes vs. no)	0.011	2.07 (0.29 - 14.57)	0.47
Chemotherapy received (yes vs. no)	0.034	5.53 (0.45 - 68.66)	0.18
Comorbidity scale (2-3 vs 0-1)**	0.61	1.67 (0.19 - 14.81)	0.64
Converted to open (yes vs. no)+	0.35	5.61 (0.17 - 187.80)	0.34
Cranial nerve XII injury (yes vs. no)	*
Free flap (yes vs. no)	*
Locoregional recurrence (yes vs. no)	0.051	12.48 (0.61 - 255.57)	0.10
Re-resections (yes vs. no)++	0.45
N stage (N2-3 vs N0-1)	0.64
p16 (positive vs negative)	0.37
RT modality (IMRT vs 2D)	>0.99
RT to primary site (yes vs. no)	>0.99
RT to ipsilateral neck (yes vs. no)	>0.99
RT to contralateral neck (yes vs. no)	>0.99
RT to all 3 sites (yes vs. no)	>0.99
RT dosage to primary site	0.67
RT dosage to ipsilateral neck	0.13
RT dosage to contralateral neck	0.14
Tumor subsite (BOT vs tonsil)	0.49	1.91 (0.27 - 13.46)	0.52
T stage (T3-4 vs. T1-2)	< 0.0001	15.38 (1.57 - 150.90)	0.019

OR = odds ratio, BOT = base of tongue, RT = radiation therapy

^*Not sufficient events for accurate analysis T stage = tumor stage, N stage = nodal stage, CN = cranial nerve, 2D = two dimensional, IMRT = intensity modulated radiation therapy

^**per ACE-27 instrument, see text for explanation

⁺conversion of the initial surgery to an open procedure for cancer clearance

⁺⁺second look surgery for revision of margins