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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Immunotherapy. 2014;6(6):755–774. doi: 10.2217/imt.14.37

Figure 1. Crystal structures of protein complexes that are involved in adhesion or costimulation during immune response.

Figure 1

An array of these molecules on the T cell and antigen-presenting cell facilitates the contact between the cells apart from TCR-MHC molecules. (A) CD2-CD58 (Protein Data Bank ID: 1AQ9), (B) B7-CTL-4 (Protein Data Bank ID: 1I8L), (C) LFA-1-ICAM-1 (Protein Data Bank ID: 1MQ8) and (D) TCR-MHC (Protein Data Bank ID: 1G6R). CTL: Cytotoxic T lymphocyte; LFA: Leukocyte function-associated antigen; TCR: T-cell receptor.