Fig. 4.

Bexarotene inhibits p38 activation after stimulation with AII. Cells were treated for 24 hours with bexarotene before stimulation with AII (10⁻⁶ M) for the indicated times. (A–C). Left panels: Representative Western blots for phospho- and total p38 (A), phospho- and total ERK (B), and phospho- and total Akt (C). β-actin was used as a loading control. N = 3 independent experiments. Right: Fold changes in densitometry measurements ± S.E.M. are shown in the graphs. *P < 0.05 versus AII DMSO at 20 minutes.