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. 2014 Oct 17;5:174. doi: 10.3389/fendo.2014.00174

Figure 1.

Figure 1

Tibial widths and epiphyseal heights are reduced in P58IPK-null mice. Radiographs and high-resolution μCT of the left limb from wild-type and null mice were used to measure tibial lengths (A), tibial epiphyseal heights (B), femoral lengths (C), and tibiae widths at the tibia/fibula intersect (D). Tibial bone density was measured close to the inferior tibio-fibular joint of wild-type and null mice (E), [Figure S1 in Supplementary Material]. Significant differences were detected by GLM ANOVA and Tukey’s post hoc test: *p ≤ 0.05; **p < 0.01; ***p < 0.001. For tibial length, width, and bone density measurements: 12–13-month-old mice n = 4 null, n = 3 wild-type and 23–25-month-old mice n = 5 null, n = 4 wild-type. For micro CT measurements: 12–13-month-old mice n = 3 null, n = 3 wild-type and 23–25-month-old mice n = 5 null, n = 4 wild-type.