Figure 1. In A, photomicrographs of lung tissue samples obtained from mice exposed to cigarette smoke, showing enlarged airspaces (EAs) resulting from alveolar consolidation during the development of pulmonary emphysema (magnification, ×40): a, control group; b, 7-day exposure group; c, 15-day exposure group; d, 30-day exposure group; e, 45-day exposure group; and f, 60-day exposure group. In B, Mean ± SEM of macrophages and neutrophils (cells/mm2). *p < 0.001 vs. control for macrophages. †p < 0.001 vs. control for neutrophils. ‡p < 0.001 vs. baseline for neutrophils.
