Figure 2. Right ventricle (RV) hypertrophy and IL-1 levels in the groups studied. In A, RV hypertrophy was determined by the ratio of RV weight to left ventricle + septum weight (LV+S). In B, IL-1 levels were determined by ELISA. *p < 0.001 (monocrotaline group vs. control and lodenafil groups for both graphs).