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. 2014 Sep 30;22(5):460–466. doi: 10.4062/biomolther.2014.056

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Copyright ©2014, The Korean Society of Applied Pharmacology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 3. — Self-administration data. Nicotine self-administration in adolescent and adult rats. (A) The number of lever responses made or (B) infusions obtained by adolescent and adult rats during the 2 h/day, 10-days nicotine SA sessions under the FR1, FR2, and FR3 schedules. Filled symbols indicate lever responses on the active lever while unfilled symbols show responses for the inactive lever. The values are presented means and S.E.M. *p<0.05, **p<0.01, ***p<0.001 statistically significant vs. the control group (Bonferroni’s posttest).